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Parkinson's disease is a neurological condition that affects the brain cells that help control movement. Over time, as these cells lose their ability to work properly, symptoms like shaking, stiff muscles, slow movements, and trouble with balance may develop. Some people also notice changes in sleep, mood, or memory.

About 1 million people in the United States and more than 10 million worldwide are living with Parkinson's. It's more common as people get older, and most cases are diagnosed in a person’s 60s. A small percentage of people develop symptoms before age 50.

While there's no cure, treatments, medications, and healthy habits like regular exercise can help people manage symptoms and stay active for many years.

Parkinson’s disease can affect anyone, but it is slightly more common in men than in women. Family history and certain environmental exposures can also play a role, but most cases happen without a clear cause.

Muhammad Ali

Muhammad Ali, widely regarded as one of the greatest boxers of all time, was diagnosed with Parkinson’s disease in 1984, just a few years after retiring from the sport. Despite the challenges that came with the condition, he became a powerful voice for Parkinson’s awareness and support. Ali helped establish the Muhammad Ali Parkinson Center in Phoenix, using his platform to inspire others and advance research. Even as the disease affected his movement and speech, he remained a global symbol of courage, resilience, and advocacy.

Alan Alda

Alan Alda, beloved actor and writer best known for his role on M*A*S*H, has been open about his experience with Parkinson’s disease, which he announced in 2018. Since then, he’s used his voice and visibility to bring attention to the condition. Alda emphasizes the importance of research and communication — particularly for patients, caregivers, and medical professionals — and supports efforts to improve understanding and care. His advocacy highlights that Parkinson’s affects not just physical movement, but also cognitive and emotional well-being.

Brian Grant

Brian Grant played 12 seasons in the National Basketball Association as a power-forward, suiting up for five teams including the Sacramento Kings, Portland Trail Blazers, and Miami Heat. He was diagnosed in 2005 at age 36 and is now very active promoting Parkinson’s awareness through the Brian Grant Foundation.